PROTAC BRD4 Degrader-9 - CAS# 2417370-42-2 ic Acid (hydrate) InChi: InChI=1S/C12H10N4OS/c1-17-11-6-14-9(5-15-11)7-2-3-8-10(4-7)18-12(13)16-8/h2-6H

InChi: InChI=1S/C12H10N4OS/c1-17-11-6-14-9(5-15-11)7-2-3-8-10(4-7)18-12(13)16-8/h2-6H

³⁶]hexapentacontan-5-yl]methyl}sulfanyl)propanoate

InChiKey: VMMVZVPAYFZNBM-KVFWHIKKSA-N

1 μM for culture supernatant and 16

PROTAC BRD4 Degrader-9 - CAS# 2417370-42-2 ic Acid (hydrate) InChi: InChI=1S/C12H10N4OS/c1-17-11-6-14-9(5-15-11)7-2-3-8-10(4-7)18-12(13)16-8/h2-6HPROTAC BRD4 Degrader 9 (compound 8a) is a PROTAC connected by ligands for von Hippel Lindau and BRD4. PROTAC BRD4 Degrader 9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0. 86 nM and 7. 6 nM, respectively. Product information CAS Number: 2417370 42 2 Molecular Weight: 1312. 50 Formula: C59H71F2N9O15S4 Chemical Name: (2S,4R) 1 [(2S) 2 (2 {2 [2 (2 {[8 (3,5 difluoropyridin 2