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CAS Number: 1374516-07-0
PubMed PMID: 27011212
Treatment of MCL cell lines with EPZ015666 led to inhibition of SmD3 methylation and cell death
resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and tumor cell apoptosis
WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 Catalog No.:M60097-2S CAS Number: 1374516-07-0WS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat