MK-8617 101slatravir Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1C3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@]4(COC)[C@H](O)C[C@@H]3OC)CC

Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1C3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@]4(COC)[C@H](O)C[C@@H]3OC)CC

Hydrolytic cleavage of the glycosidic bond

Chemical Name: {7-[2-(2-amino-1

Smiles: CC(C)[C@H](NC(=O)[C@H](CC1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N[C@@H](CCC(N)=O)C(O)=O

MK-8617 101slatravir Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1C3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@]4(COC)[C@H](O)C[C@@H]3OC)CCMK 8617 is an orally active pan inhibitor of hypoxia inducible factor prolyl hydroxylase 1 3 (HIF PHD1 3) with an IC50 of 1 nM for PHD2. Product information CAS Number: 1187990 87 9 Molecular Weight: 443. 45 Formula: C24H21N5O4 Chemical Name: N [bis(4 methoxyphenyl)methyl] 4 hydroxy 2 (pyridazin 3 yl)pyrimidine 5 carboxamide Smiles: COC1C=CC(=CC=1)C(NC(=O)C1=CN=C(N=C1O)C1C=CC=NN=1)C1C=CC(=CC=1)OC InChiKey: WXLPERVDMILVIF UHFFFAOYSA N InChi: InChI=1S