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[Effects of glycogen synthase kinase 3β overexpression in rat and glycogen synthase kinase 3β inhibitor SB-216763 on proliferation of hepatic oval cells]
And the IC50 values are 775 nM
CC1N=CSC=1C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN)C(C)(C)C)C=C1
ClH/c1-10(27)25(26)7-13-18(16(8-25)35-17-6-14(28)15(29)9-34-17)24(33)20-19(23(13)32)21(30)11-4-2-3-5-12(11)22(20)31
4-Hydroperoxy cyclophosphamide Catalog No.:M12466-10 [Effects of glycogen synthase kinase4 Hydroperoxy cyclophosphamide is the active metabolite form of the prodrug Cyclophosphamide. 4 Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4 Hydroperoxy cyclophosphamide has the potential for lymphomas and autoimmune disorders. Product information CAS Number: 39800 16 3 Molecular