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Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery
PBTZ-169 has improved potency
1533426-72-0
Analytical comparison of natural and pharmaceutical ventricular myosin activators
ML224 - CAS# 1338824-21-7 60328 Applications of frontal affinity chromatographyML224, also known as NCGC00242364 and ANTAG3, CAS No. 1338824 21 7, is a selective TSHR inverse agonist; inhibits TSH stimulated cAMP production with an IC50 = 2. 3 M. ML224 could be a useful tool for studying TSHR functions; it could also be a potential lead for development of drugs to treat TSHR mediated hyperthyroidism caused by constitutively activating mutations or stimulating auto antibodies associated with Graves disease. Product information