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8(12):e83310
InChiKey: AYUQICXJAMPXPF-UHFFFAOYSA-N
3-d]pyrano[4'
and kaliuresis
N-(3-hydroxyphenyl)-Arachidonoyl amide isqualic acid 8(12):e83310IC50: 2 M N (3 hydroxyphenyl) Arachidonoyl amide, also known as 3 HPAA, is an analog of AM404 (N (4 hydroxyphenyl) arachidonoyl amide), a selective inhibitor of carrier mediated transport of arachidonoyl ethanolamide. 3 HPAA, metabolized by both cyclooxygenase (COX) 1 and COX 2, is an irreversible and selective inhibitor of COX 2 with an IC50 value of 2 M. 3 HPAA can be efficiently oxygenated to prostaglandin and hydroxyeicosatetraenoate products by
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