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PubMed Central PMCID: PMC4309183
Molecular Weight: 525
Chemical Name: N-(3-bromophenyl)-6
exhibiting ATP-competitive inhibition kinetics
ABT-888 dihydrochloride - CAS# 912445-05-7 0109 PubMed Central PMCID: PMC4309183ABT 888 dihydrochloride, also known asVeliparib, CAS No. 912445 05 7, is a potent and selective Poly (ADP Ribose) Polymerase (PARP) Inhibitor. ABT 888 dihydrochloride enhances apoptosis and autophagy in response to treatments that cause DNA breaks, including radiation and DNA alkylation. ABT 888 dihydrochloride is an orally bioavailable inhibitor of PARP1 and PARP2 (Kis = 5. 2 and 2. 9 nM, respectively). Product information CAS Number: 912445 05 7
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