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SKA-121 displays 41-fold selectivity for KCa3
Arnebin-1 promotes angiogenesis by inducing eNOS
InChiKey: NJJDBBUWWOAOLD-CFBAGHHKSA-N
19-trioxapentacyclo[10
Arylquin 1 Catalog No.:M22552-C SKA-121 displays 41-fold selectivity forArylquin 1 is a potent secretagogue of the tumor suppressor protein prostate apoptosis response 4 (Par 4). Par 4 is ubiquitously expressed in normal cells and tissues, but it is inactivated, downregulated or mutated in several types of cancers. Par 4 can selectively induce cancer cell apoptosis but not normal cells. Both intracellular and secreted Par 4 have a role in apoptosis induction by caspase dependent mechanisms. In vitro: Previous study showed
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