bis(7)-Tacrine Catalog No.:M22824-C 21)22)4-23-5-1-2-8(24)6(3-5)14(25)26/h1-3

21)22)4-23-5-1-2-8(24)6(3-5)14(25)26/h1-3

but does not affect normal gastric emptying or feeding in intact rats

InChi: InChI=1S/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23(2

Smiles: CC(C)(O)C1=CC=CC(=N1)N1C2=NC(NC3=CC4CN(C)CC5(CC5)C=4C=C3)=NC=C2C(=O)N1CC=C

bis(7)-Tacrine Catalog No.:M22824-C 21)22)4-23-5-1-2-8(24)6(3-5)14(25)26/h1-3IC50: 0. 40 nM bis(7) Tacrine is an AChE inhibitor. Acetylcholinesterase ( AChE), the primary cholinesterase in the body, is an enzyme catalyzing the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. In vitro: bis(7) Tacrine, the 9 amino 1,2,3,4 tetrahydroacridine (THA) dimer, was identified as a promising drug candidate for the palliative treatment of Alzheimer's disease, due to its significant