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Two indolocarbazole alkaloids with apoptosis activity from a marine-derived actinomycete Z2039-2 Arch
Cilomilast and (R)-rolipram are equipotent at suppressing LPS-induced TNF-α formation with -log (IC50) of 7
in contrast with the 100 mg/kg dose
PubMed PMID: 18930822
Netupitant metabolite Monohydroxy Netupitant Catalog No.:M8234-10 Two indolocarbazole alkaloids with apoptosisMonohydroxy Netupitant is the metabolite of Netupitant which is a potent and selective neurokinin 1 receptor (NK1) receptor antagonist. It is achiral and orally active. Product information CAS Number: 910808 12 7 Molecular Weight: 594. 59 Formula: C30H32F6N4O2 Synonym: Monohydroxy Netupitant Chemical Name: 2 [3,5 bis(trifluoromethyl)phenyl] N {4 [2 (hydroxymethyl)phenyl] 6 (4 methylpiperazin 1 yl)pyridin 3 yl} N,2 dimethylpropanamide Smiles:
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