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Bergamottin e alcohol 4C6H13N/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33

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Description

4C6H13N/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33

Four LNCaP xenograft arms each with 12 mice are dosed intraperitoneally with DMSO (control) or Erlotinib 80 mg/kg or Amuvatinib (MP470) 50 mg/kg or Erlotinib 80 mg/kg plus Amuvatinib 50 mg/kg daily for 2 weeks and then observed for a further 11 days

with a pA2 value of 5

InChiKey: OTGPYEHFRKGRIZ-UHFFFAOYSA-N

Bergamottin e alcohol 4C6H13N/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10. 703 nM. Product information CAS Number: 7380 40 7 Molecular Weight: 338. 40 Formula: C21H22O4 Chemical Name: 4 {[(2E) 3,7 dimethylocta 2,6 dien 1 yl]oxy} 7H furo[3,2 g]chromen 7 one Smiles: CC(C)=CCC C( C)=C COC1C2C=COC=2C=C2OC(=O)C=CC2=1 InChiKey: DBMJZOMNXBSRED OQLLNIDSSA N InChi: InChI=1S C21H22O4 c1 14(2)5 4 6 15(3)9 11 24 21 16 7 8 20(22)25 19(16)13 18 17(21)10 12 23 18

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