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118(4):1289-1297
InChiKey: KSERXGMCDHOLSS-LJQANCHMSA-N
52(2):13-21
ID-8 (10 μM) stimulates ESCs proliferation in serum-free media for more than 1 month
FTI-277 Hydrochloride Size:Solid 10 mg 118(4):1289-1297FTI 277 is a peptide mimetic of the COOH terminal Cys Val Ile Met of K Ras4B that inhibited potently FTase in vitro (IC50 = 500 pM) and was highly selective for FTase over geranylgeranyltransferase I (GGTase I) (IC50 = 50 nM). FTI 277, the methyl ester derivative of FTI 276, was extremely potent (IC50 = 100 nM) at inhibiting H Ras, but not the geranylgeranylated Rap1A processing in whole cells. Product information CAS Number: 180977 34 8 Molecular
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