Compound E Catalog No.:M13053-2 InChi: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10

InChi: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10

382 μM for A2780 cell lines)

that showed good ADME and PK properties

InChi: InChI=1S/C15H12N2O5S/c1-21-15(18)11(9-16)8-12-4-7-14(22-12)10-2-5-13(6-3-10)23(17

Compound E Catalog No.:M13053-2 InChi: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10Compound E is a secretase inhibitor. Compound E bloks amyloid(40), amyloid(42), and Notch secretase cleavage with IC50s of 0. 24, 0. 37, 0. 32 nM, respectively. Product information CAS Number: 209986 17 4 Molecular Weight: 490. 50 Formula: C27H24F2N4O3 Chemical Name: (2S) 2 [2 (3,5 difluorophenyl)acetamido] N [(3S) 1 methyl 2 oxo 5 phenyl 2,3 dihydro 1H 1,4 benzodiazepin 3 yl]propanamide Smiles: