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Most KRAS oncoproteins cycle between an active state and an inactive state in cancer cells and are dependent on nucleotide exchange for activation
the encoded protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism
Sporadic and familial mutations in this gene result in paragangliomas
Most Caucasians have two major isozymes
ITGB3 rabbit monoclonal antibody package:50 μl Most KRAS oncoproteins cycle betweenSpecification Full name ITGB3 rabbit monoclonal antibody Alternative names 50 l 100 l Reactivity rabbit monoclonal Applications WB Host Rabbit Clone type rabbit monoclonal Target Background The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along