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IHC Host Rabbit Clone type rabbit polyclonal Target Background Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway
Defects in this gene are a cause of spastic paraplegia
Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region
Change the gradient ethanol regularly to ensure the purity
BRAT1 rabbit monoclonal antibody package:50 μl IHC Host Rabbit Clone typeSpecification Full name BRAT1 rabbit monoclonal antibody Alternative names 50 l 100 l Reactivity rabbit monoclonal Applications WB, IF Host Rabbit Clone type rabbit monoclonal Target Background The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling