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It was the plane that gave us Glimpse of Nature, so theres still hope

This answer is always going to vary a little bit, depending on the colors of your deck (and by extension, the tutors you have access to), your decks strategy, and the power level youre shooting for

In a way, you choose what to proliferate by choosing which permanents or players to increase the counters on

For example, if your commander has the ability to gain a lot of life, you might build a Commander deck with cards that benefit from maintaining as high a life total as possible, and focus on out-enduring your foes - or you might use your life total as a resource, burning through it to fuel powerful abilities and relying on your commander to keep yourself from succumbing