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It doesn't see much play outside of Toxic, but it is a great top-end for the deck to clear the battlefield of a blocker to get those last few poison counters and saw great success there
You can either make a 2/2 White Cat Beast token, which is nice but not what were going for, or you can put a +1/+1 counter on each Creature you control and then those Creatures gain vigilance until end of turn
Reds options are a bit more limited, getting access to rummage effects (allowing players to draw cards if they discard first) or temporary card advantage effects like [card]Prophetic Flamespeaker[/card]