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Riku of Two Reflections Since Riku of Two Reflectionss ability triggers when a creature enters, you can use cards like Thassa, Deep-Dwelling and Essence Flux to generate many copies of one card

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You can also interact with uncounterable spells with other spells that dont use the word counter. This gives some players a chance to circumnavigate the cant be countered ability with cards like Obscura Interceptor

Notions of contagion date to the Renaissance at the earliest (see miasma theory above), and germ theory came after contagion as a concept